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bioregistry

Integrated registry of biological databases and nomenclatures

bioregistry v0.14.0 173.1K downloads/30d#10,317 on PyPI146
Permissive license MIT Active released

What it is and what it does

Bioregistry is a community-maintained meta-registry that aggregates metadata about life science databases, ontologies, and persistent identifier systems. It provides Python functions to normalize biological prefixes (handling case variations and synonyms), parse CURIEs into normalized prefix-identifier pairs, and convert between CURIEs and IRIs using a comprehensive registry of provider URL patterns.

The package is designed for developers working with biological data who need to standardize identifier formats across heterogeneous sources. It handles common prefix variations found in OBO Foundry ontologies, MIRIAM, and other life science standards, and can parse IRIs from OLS, identifiers.org, and other well-known providers back into canonical CURIEs. The underlying registry is automatically updated daily and includes weekly health checks to verify that provider URLs remain functional.

Use it for:

  • Normalize biological identifiers from different sources (e.g., 'CHEBI' → 'chebi', 'taxonomy' → 'ncbitaxon')
  • Parse a CURIE string into its canonical prefix and local identifier components
  • Convert between CURIE and IRI representations for biological resources
  • Resolve ambiguous or misspelled biological database prefixes to their canonical forms
  • Integrate identifier handling into bioinformatics pipelines that work with multiple ontologies

Worth the install?

AI-flagged interpretation of the facts on this page — verify before relying

Bioregistry provides a unified Python interface to query, normalize, and parse identifiers and CURIEs across life science databases, ontologies, and other biological resources.

Yes. Bioregistry is actively maintained, has no known vulnerabilities, supports current Python versions (3.11+), and solves a real problem in bioinformatics: standardizing identifiers across fragmented biological databases. Low install friction and permissive licensing make it a straightforward addition to life science projects.

Install

bioregistry on PyPI

pip

pip install bioregistry

uv

uv add bioregistry

poetry

poetry add bioregistry

Installing bioregistry

Before you install

Low friction installation with 11 runtime dependencies, all standard Python packages. Actively maintained with daily automated updates and weekly health checks; last release 4 days ago.

License in practice

MIT license (permissive) allows free use, modification, and distribution. Manually curated data are available under CC0 1.0 Universal; aggregated data redistributed under their original licenses.

Quickstart

pip install bioregistry

from bioregistry import normalize_prefix, parse_curie, normalize_curie

# Normalize a prefix variant
assert "chebi" == normalize_prefix("CHEBI")

# Parse a CURIE
assert ("chebi", "1234") == parse_curie("chebi:1234")

# Normalize a full CURIE
assert "chebi:1234" == normalize_curie("CHEBI:1234")

Verify before relying

  • Whether the package supports querying remote Bioregistry endpoints or only works with local/bundled data
  • Performance characteristics when working with the full registry of prefixes and identifiers

Package facts

License MIT (permissive)
Python support supports the current Python release (>=3.11)
Install friction low — pure-Python wheel
Runtime dependencies 11 — requests, tqdm, pystow, click, more-click, pydantic, curies, sssom-pydantic, urllib3, python-multipart, idna
Maintenance actively maintained — 4 days since the last release
Last repo commit
First released
Downloads 173,068/month — #10,317 on PyPI (30-day window, as of 2026-08-14)
Known vulnerabilities none known (OSV.dev, checked 2026-08-14)

Evidence: bioregistry-0.14.0-py3-none-any.whl

Keywords: snekpack, cookiecutter, databases, biological databases, biomedical databases, persistent identifiers

Development Status :: 4 - BetaEnvironment :: ConsoleFramework :: PytestFramework :: SphinxFramework :: toxIntended Audience :: DevelopersOperating System :: OS IndependentProgramming Language :: PythonProgramming Language :: Python :: 3 :: OnlyProgramming Language :: Python :: 3.11Programming Language :: Python :: 3.12Programming Language :: Python :: 3.13Programming Language :: Python :: 3.14

Tags

biological identifier normalizationCURIE parsing life sciencedatabase prefix registryontology identifier resolutionpersistent identifier lookupbiomedical database registryIRI to CURIE conversion
bioinformaticsidentifier-normalizationontology

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