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biom-format

Biological Observation Matrix (BIOM) format

With conditionsPyPI Python ModulesReleased Aug 2025134.2K downloads / moBSDPlatform wheel

Decision gist · record as of 2026-08-14

platform wheels — biom_format-2.1.17-cp310-cp310-macosx_10_9_x86_64.whl · biom_format-2.1.17-cp310-cp310-macosx_11_0_arm64.whl · biom_format-2.1.17-cp310-cp310-manylinux_2_17_aarch64.manylinux2014_aarch64.whl
v2.1.17 · released 2025-08-26 · Python >=3.9 · 5 runtime deps: click, numpy, scipy, pandas, h5py

Yes, if you work with microbiome or metagenomic data in BIOM format. The package is stable, permissively licensed, and widely compatible across platforms and Python versions. However, maintenance is aging (last release 353 days ago), so verify that it meets your specific pipeline requirements before committing to it for production workflows. No known security vulnerabilities.AI-flagged interpretation of the facts on this page — verify before relying

Before you install

  • Requires h5py, which depends on HDF5 system libraries; installation may require a C compiler or prebuilt wheels for your platform.
  • Medium install friction due to compiled dependencies (numpy, scipy, h5py).
  • Wheels available for Python 3.9–3.13 on macOS, Linux, and Windows.

License · maintenance · safety

BSD (permissive) — BSD license is permissive; you may use, modify, and distribute this package freely in commercial and private projects with minimal restrictions.

last release 2025-08-26 (353 days)

0 known vulnerabilities (OSV.dev, 2026-08-14) · 134,204 downloads/mo, #11,483 on PyPI

Verify before relying

pip install biom-format

import biom
table = biom.load_table('data.biom')
print(table.shape)
  • Whether the package actively maintains compatibility with major microbiome analysis pipelines.
  • Performance characteristics for large matrices.
  • Availability of comprehensive documentation beyond the homepage.
Same gist for agents: .md · .json

What it is and what it does

biom-format is a Python library for working with the BIOM (Biological Observation Matrix) file format, a standard in microbiome and metagenomic research for storing abundance data—counts of observations such as OTUs, KO categories, or lipid types across multiple biological samples. It provides read/write access to BIOM files, typically in HDF5 format, and allows you to load, manipulate, and export these matrices for downstream analysis.

The package depends on numpy, scipy, pandas, h5py, and click, making it suitable for integration into data pipelines. It supports Python 3.9 through 3.13 on major platforms. The library is designed to be a general-purpose container for observation counts from various high-throughput biological assays.

Use it for

  • Load and parse BIOM files from microbiome pipelines for downstream statistical analysis.
  • Convert between BIOM and tabular formats for integration with other analysis tools.
  • Manipulate sample metadata and observation taxonomy within a BIOM matrix programmatically.
  • Export abundance tables from your own analysis pipeline in the standard BIOM format.
  • Batch process multiple BIOM files to extract subsets of samples or observations.

Worth the install?

AI-flagged interpretation of the facts on this page. Verify before relying on it.

With conditions

Yes, if you work with microbiome or metagenomic data in BIOM format.

The package is stable, permissively licensed, and widely compatible across platforms and Python versions. However, maintenance is aging (last release 353 days ago), so verify that it meets your specific pipeline requirements before committing to it for production workflows. No known security vulnerabilities.

Install

biom-format on PyPI

Before you install

Medium install friction due to compiled dependencies (numpy, scipy, h5py). Wheels available for Python 3.9–3.13 on macOS, Linux, and Windows. Last release 353 days ago; maintenance status is aging, so expect slower response to issues.

Requires h5py, which depends on HDF5 system libraries; installation may require a C compiler or prebuilt wheels for your platform.

License in practice

BSD license is permissive; you may use, modify, and distribute this package freely in commercial and private projects with minimal restrictions.

Quickstart

pip install biom-format

import biom
table = biom.load_table('data.biom')
print(table.shape)

Verify before relying

  • Whether the package actively maintains compatibility with major microbiome analysis pipelines.
  • Performance characteristics for large matrices.
  • Availability of comprehensive documentation beyond the homepage.

Package facts

LicenseBSD permissive
Python supportSupports the current Python release >=3.9
Install frictionMedium. Platform-specific wheel
Runtime dependencies
5 packages
clicknumpyscipypandash5py
MaintenanceAging 353 days since the last release
First released
Downloads134,204 / month, #11,483 on PyPI 30-day window, as of 2026-08-14
Known vulnerabilitiesNone known OSV.dev, checked 2026-08-14
Classifiers
Development Status :: 4 - BetaLicense :: OSI Approved :: BSD LicenseOperating System :: MacOS :: MacOS XOperating System :: Microsoft :: WindowsOperating System :: OS IndependentOperating System :: POSIX :: LinuxProgramming Language :: PythonProgramming Language :: Python :: 3Programming Language :: Python :: 3 :: OnlyProgramming Language :: Python :: 3.10Programming Language :: Python :: 3.11Programming Language :: Python :: 3.12Programming Language :: Python :: 3.13Programming Language :: Python :: 3.9Programming Language :: Python :: Implementation :: CPythonTopic :: Scientific/Engineering :: Bio-InformaticsTopic :: Software Development :: Libraries :: Application FrameworksTopic :: Software Development :: Libraries :: Python Modules

Evidence: biom_format-2.1.17-cp310-cp310-macosx_10_9_x86_64.whl; biom_format-2.1.17-cp310-cp310-macosx_11_0_arm64.whl; biom_format-2.1.17-cp310-cp310-manylinux_2_17_aarch64.manylinux2014_aarch64.whl; biom_format-2.1.17-cp310-cp310-manylinux_2_5_x86_64.manylinux1_x86_64.manylinux_2_17_x86_64.manylinux2014_x86_64.whl; biom_format-2.1.17-cp310-cp310-win_amd64.whl; biom_format-2.1.17-cp311-cp311-macosx_10_9_x86_64.whl; biom_format-2.1.17-cp311-cp311-macosx_11_0_arm64.whl; biom_format-2.1.17-cp311-cp311-manylinux_2_17_aarch64.manylinux2014_aarch64.whl; biom_format-2.1.17-cp311-cp311-manylinux_2_5_x86_64.manylinux1_x86_64.manylinux_2_17_x86_64.manylinux2014_x86_64.whl; biom_format-2.1.17-cp311-cp311-win_amd64.whl; biom_format-2.1.17-cp312-cp312-macosx_10_13_x86_64.whl; biom_format-2.1.17-cp312-cp312-macosx_11_0_arm64.whl; biom_format-2.1.17-cp312-cp312-manylinux_2_17_aarch64.manylinux2014_aarch64.whl; biom_format-2.1.17-cp312-cp312-manylinux_2_5_x86_64.manylinux1_x86_64.manylinux_2_17_x86_64.manylinux2014_x86_64.whl; biom_format-2.1.17-cp312-cp312-win_amd64.whl; biom_format-2.1.17-cp313-cp313-macosx_10_13_x86_64.whl; biom_format-2.1.17-cp313-cp313-macosx_11_0_arm64.whl; biom_format-2.1.17-cp313-cp313-manylinux_2_17_aarch64.manylinux2014_aarch64.whl; biom_format-2.1.17-cp313-cp313-manylinux_2_5_x86_64.manylinux1_x86_64.manylinux_2_17_x86_64.manylinux2014_x86_64.whl; biom_format-2.1.17-cp313-cp313-win_amd64.whl

Tags

Capabilities
biom format reader writermicrobiome data matrixotu abundance tablebiological observation matrixbiom file parsersample observation countsmetagenomics data format
Topics
bioinformaticsmicrobiomedata-format

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See also scikit-bio · bionty · biotite · deepbiop · biocommons.seqrepo · peppy · bio · python-libsbml · bioversions · mudata