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neo

Neo is a package for representing electrophysiology data in Python, together with support for reading a wide range of neurophysiology file formats

Worth itPyPI Scientific/EngineeringReleased Jun 2026126.4K downloads / moBSD-3-ClausePure Python

Decision gist · record as of 2026-08-14

pure-Python wheel — neo-0.14.5-py3-none-any.whl
v0.14.5 · released 2026-06-25 · Python >=3.10 · 3 runtime deps: packaging, numpy, quantities

Yes. Neo is actively maintained, has no known security vulnerabilities, uses a permissive license, and is the de facto standard data model for electrophysiology in Python. Install it if you work with neural recordings, need to read multiple file formats, or want to integrate with other neuroscience tools that depend on Neo's object model.AI-flagged interpretation of the facts on this page — verify before relying

Before you install

  • Requires Python 3.10 or later; numpy and quantities packages must be installed as runtime dependencies.
  • Installation is straightforward with low friction; the package has three runtime dependencies (packaging, numpy, quantities) and is actively maintained with a recent release within the last 50 days.

License · maintenance · safety

BSD-3-Clause (permissive) — BSD-3-Clause is permissive, allowing commercial use, modification, and distribution with minimal restrictions beyond retaining the license notice.

last release 2026-06-25 (50 days) · last repo commit 2026-08-11 · 362 stars

0 known vulnerabilities (OSV.dev, 2026-08-14) · 126,420 downloads/mo, #11,776 on PyPI

Verify before relying

pip install neo

import neo
block = neo.Block(name="recording")
segment = neo.Segment(name="trial_1")
block.segments.append(segment)
  • Whether the package supports reading and writing all listed formats equally well or if some are read-only.
  • Performance characteristics when working with large multi-electrode datasets.
  • Whether unit conversion and dimensional consistency checks have measurable overhead.
Same gist for agents: .md · .json

What it is and what it does

Neo is a data representation layer for electrophysiology research, built on top of NumPy and the quantities package to add physical units and dimensional consistency to neural recording data. It defines a hierarchical object model (Block, Segment, ChannelIndex, Unit, etc.) that maps naturally to intracellular, extracellular, and multi-electrode recordings, and provides I/O support for both proprietary formats (Spike2, Plexon, Blackrock, Tdt, AlphaOmega, NeuroExplorer, Axon) and open formats like HDF5.

Neo is deliberately designed as a lightweight data container with no analysis or visualization functions—its role is to standardize how electrophysiology data is represented so that other tools (like Elephant for analysis, SpykeViewer for visualization, or PyNN for simulations) can work with a common object model. Data stored in Neo objects behave like NumPy arrays but carry metadata, enforce unit compatibility, and support automatic conversion between measurement scales.

Use it for

  • Load multi-format neurophysiology recordings into a single standardized Python object for downstream analysis pipelines.
  • Convert between proprietary spike recording formats (Spike2, Plexon, Blackrock) to enable cross-platform data sharing.
  • Build analysis workflows that accept Neo data objects from multiple recording systems without format-specific parsing code.
  • Store electrophysiology data with physical units and dimensional metadata to prevent unit conversion errors in calculations.
  • Integrate electrophysiology data with simulation frameworks like PyNN that expect Neo-compatible data structures.

Worth the install?

AI-flagged interpretation of the facts on this page. Verify before relying on it.

Worth it

Yes.

Neo is actively maintained, has no known security vulnerabilities, uses a permissive license, and is the de facto standard data model for electrophysiology in Python. Install it if you work with neural recordings, need to read multiple file formats, or want to integrate with other neuroscience tools that depend on Neo's object model.

Install

neo on PyPI

Before you install

Installation is straightforward with low friction; the package has three runtime dependencies (packaging, numpy, quantities) and is actively maintained with a recent release within the last 50 days.

Requires Python 3.10 or later; numpy and quantities packages must be installed as runtime dependencies.

License in practice

BSD-3-Clause is permissive, allowing commercial use, modification, and distribution with minimal restrictions beyond retaining the license notice.

Quickstart

pip install neo

import neo
block = neo.Block(name="recording")
segment = neo.Segment(name="trial_1")
block.segments.append(segment)

Verify before relying

  • Whether the package supports reading and writing all listed formats equally well or if some are read-only.
  • Performance characteristics when working with large multi-electrode datasets.
  • Whether unit conversion and dimensional consistency checks have measurable overhead.

Package facts

LicenseBSD-3-Clause permissive
Python supportSupports the current Python release >=3.10
Install frictionLow. Pure-Python wheel
Runtime dependencies
3 packages
packagingnumpyquantities
MaintenanceActively maintained 50 days since the last release
Last repo commit
First released
Downloads126,420 / month, #11,776 on PyPI 30-day window, as of 2026-08-14
Known vulnerabilitiesNone known OSV.dev, checked 2026-08-14
Classifiers
Development Status :: 4 - BetaIntended Audience :: Science/ResearchNatural Language :: EnglishOperating System :: OS IndependentProgramming Language :: Python :: 3Programming Language :: Python :: 3 :: OnlyProgramming Language :: Python :: 3.10Programming Language :: Python :: 3.11Programming Language :: Python :: 3.12Programming Language :: Python :: 3.13Topic :: Scientific/Engineering

Evidence: neo-0.14.5-py3-none-any.whl

Tags

Capabilities
electrophysiology data formatneurophysiology file readerEEG data modelspike recording datamulti-electrode data structureneural data interchangebrain recording file formats
Topics
neuroscienceelectrophysiologydata-format

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See also mne-bids · pynwb · mne · nibabel · nilearn · pyEDFlib · edfio · pybids · fiftyone-brain · nipype