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ete3

A Python Environment for (phylogenetic) Tree Exploration

With conditionsPyPI Python ModulesReleased May 2023100.4K downloads / moGPLv3Source build

Decision gist · record as of 2026-08-14

sdist only — ete3-3.1.3.tar.gz · builds from source
v3.1.3 · released 2023-05-02

Yes, if you work in phylogenetics or genomics and need tree manipulation and visualization. The package is mature, actively maintained, and well-established in its domain. However, be prepared for high installation friction (likely system dependencies), verify Python version compatibility before installing, and ensure GPLv3 licensing aligns with your project's constraints.AI-flagged interpretation of the facts on this page — verify before relying

Before you install

  • High install friction suggests system libraries or build tools may be required; Qt support may require additional X11 or graphical environment setup on some systems.
  • Installation friction is high; the package ships as a source tarball and has no declared runtime dependencies, suggesting compiled components or system-level prerequisites may be required during build.

License · maintenance · safety

GPLv3 (copyleft) — GPLv3 copyleft license means any derivative work or distribution must also be open-source under compatible terms; suitable for research and open-source projects but requires careful review before use in proprietary software.

last release 2023-05-02 (1200 days) · last repo commit 2026-06-01 · 885 stars

0 known vulnerabilities (OSV.dev, 2026-08-14) · 100,419 downloads/mo, #12,985 on PyPI

Verify before relying

pip install ete3
from ete3 import Tree
t = Tree('(A:1,B:1)C;')
print(t)
  • What system libraries or compiled dependencies are needed at build time (the high friction suggests non-trivial prerequisites).
  • Whether Qt support (listed in classifiers) is optional or required, and what additional setup it demands.
  • Current Python version compatibility (requires_python is unspecified in the metadata).
Same gist for agents: .md · .json

What it is and what it does

ETE3 is a mature Python toolkit for phylogenetic tree work, supporting reconstruction, manipulation, analysis, and visualization of tree-structured data. It is primarily designed for researchers in phylogenetics and genomics, though it can handle any tree-like data structure. The package has been actively maintained since its first release in 2015 and is currently at version 3.1.3, with a repository showing recent activity and a moderate user base.

The toolkit provides both programmatic APIs for tree operations and visualization capabilities, including support for Qt-based graphical output. Installation carries high friction, indicating the presence of compiled dependencies or system-level requirements that may need manual setup. The codebase is mature and stable, and the package is widely used in the bioinformatics community, though users should be aware of the GPLv3 copyleft licensing constraint.

Use it for

  • Reconstruct and manipulate phylogenetic trees from sequence alignment or distance data in genomics research.
  • Visualize and compare evolutionary relationships between organisms or genes in publication-quality formats.
  • Analyze tree topology, branch lengths, and clustering patterns programmatically in bioinformatics pipelines.
  • Convert between tree file formats (Newick, NHX, etc.) and perform tree-to-tree comparisons.
  • Build custom tree-based analyses by scripting tree traversal and node manipulation in Python.

Worth the install?

AI-flagged interpretation of the facts on this page. Verify before relying on it.

With conditions

Yes, if you work in phylogenetics or genomics and need tree manipulation and visualization.

The package is mature, actively maintained, and well-established in its domain. However, be prepared for high installation friction (likely system dependencies), verify Python version compatibility before installing, and ensure GPLv3 licensing aligns with your project's constraints.

Install

ete3 on PyPI

Before you install

Installation friction is high; the package ships as a source tarball and has no declared runtime dependencies, suggesting compiled components or system-level prerequisites may be required during build.

High install friction suggests system libraries or build tools may be required; Qt support may require additional X11 or graphical environment setup on some systems.

License in practice

GPLv3 copyleft license means any derivative work or distribution must also be open-source under compatible terms; suitable for research and open-source projects but requires careful review before use in proprietary software.

Quickstart

pip install ete3
from ete3 import Tree
t = Tree('(A:1,B:1)C;')
print(t)

Verify before relying

  • What system libraries or compiled dependencies are needed at build time (the high friction suggests non-trivial prerequisites).
  • Whether Qt support (listed in classifiers) is optional or required, and what additional setup it demands.
  • Current Python version compatibility (requires_python is unspecified in the metadata).

Package facts

LicenseGPLv3 copyleft
Python supportNot specified
Install frictionHigh. Source build required
Runtime dependenciesNone
MaintenanceActively maintained 1,200 days since the last release
Last repo commit
First released
Downloads100,419 / month, #12,985 on PyPI 30-day window, as of 2026-08-14
Known vulnerabilitiesNone known OSV.dev, checked 2026-08-14
Classifiers
Development Status :: 6 - MatureEnvironment :: ConsoleEnvironment :: X11 Applications :: QtIntended Audience :: DevelopersIntended Audience :: Other AudienceIntended Audience :: Science/ResearchLicense :: OSI Approved :: GNU General Public License (GPL)Natural Language :: EnglishOperating System :: MacOSOperating System :: Microsoft :: WindowsOperating System :: POSIX :: LinuxProgramming Language :: PythonTopic :: Scientific/Engineering :: Bio-InformaticsTopic :: Scientific/Engineering :: VisualizationTopic :: Software Development :: Libraries :: Python Modules

Evidence: ete3-3.1.3.tar.gz

Tags

Capabilities
phylogenetic tree visualizationtree reconstruction pythonphylogenomics analysistree manipulation librarybioinformatics tree toolstree comparison analysisphylogeny data exploration
Topics
phylogeneticsbioinformaticstree-analysis
PyPI keywords
treetree reconstructiontree visualizationtree comparisonphylogenyphylogeneticsphylogenomics

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See also biopython · dtreeviz · ai-edge-model-explorer · nutree · pyranges · scikit-bio · py_trees · anytree · open3d · asciitree