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dipy

Diffusion MRI Imaging in Python

dipy v1.12.1 100.8K downloads/30d#12,972 on PyPI835
Permissive license Unless otherwise specified by LICENSE.txt files in individual directories, or within individual files or functions, all code is: Copyright (c) 2008-2026, dipy developers All rights reserved.… (full text in the JSON record) Active released

What it is and what it does

DIPY is a specialized neuroimaging library for processing and analyzing diffusion magnetic resonance imaging (dMRI) data. It provides implementations of diffusion tensor imaging (DTI), tractography algorithms, fiber tracking, brain registration, segmentation, and microstructural analysis techniques commonly used in neuroscience research.

The library is built on top of numpy, scipy, and nibabel, and integrates with h5py for data I/O. It is designed for research workflows and explicitly disclaims clinical use without contacting the maintainers. The package follows Scientific Python's SPEC 0 versioning guidelines and maintains active development with broad platform support.

Use it for:

  • Perform fiber tractography and white matter bundle segmentation from diffusion-weighted MRI scans.
  • Compute diffusion tensor metrics (FA, MD, RD, AD) for microstructural brain analysis.
  • Register diffusion images to standard brain templates for group-level statistical analysis.
  • Simulate diffusion signals for validation and testing of reconstruction algorithms.
  • Extract connectome data and perform network analysis on tractography results.

Worth the install?

AI-flagged interpretation of the facts on this page — verify before relying

DIPY is a Python library for analyzing diffusion MRI data, providing tools for tractography, fiber tracking, registration, and microstructural analysis of brain diffusion imaging.

Yes, if you work with diffusion MRI data in a research context. DIPY is actively maintained, well-established (since 2011), and has no known vulnerabilities. Medium install friction is typical for scientific packages with compiled dependencies. Not suitable for clinical deployment without explicit approval from maintainers. Install via pip or conda; prebuilt wheels available for modern Python versions.

Install

dipy on PyPI

pip

pip install dipy

uv

uv add dipy

poetry

poetry add dipy

Installing dipy

Before you install

Medium install friction due to compiled dependencies (numpy, scipy, nibabel, h5py). Active maintenance with recent releases; last commit 2026-08-11. Supports Python 3.11 through 3.14 with prebuilt wheels across macOS, Linux, and Windows platforms.

License in practice

BSD license (permissive). You may use, modify, and distribute DIPY freely in commercial or private projects provided you retain copyright notices and disclaimers. No patent indemnification or warranty.

Quickstart

pip install dipy

import dipy
from dipy.data import get_fnames
from dipy.io.image import load_nifti

hardi_fname, hardi_bval, hardi_bvec = get_fnames('stanford_hardi')
data, affine = load_nifti(hardi_fname)

Requires compiled dependencies (numpy, scipy, nibabel, h5py); installation may take several minutes on first setup.

Verify before relying

  • Whether clinical deployment support exists despite the stated research-only disclaimer.
  • Performance characteristics and scalability limits for large diffusion datasets.
  • Availability of GPU acceleration or parallel processing capabilities.

Package facts

License Unless otherwise specified by LICENSE.txt files in individual directories, or within individual files or functions, all code is: Copyright (c) 2008-2026, dipy developers All rights reserved.… (full text in the JSON record) (permissive)
Python support supports the current Python release (>=3.11)
Install friction medium — platform-specific wheel
Runtime dependencies 7 — numpy, scipy, nibabel, h5py, packaging, tqdm, trx-python
Maintenance actively maintained — 113 days since the last release
Last repo commit
First released
Downloads 100,810/month — #12,972 on PyPI (30-day window, as of 2026-08-14)
Known vulnerabilities none known (OSV.dev, checked 2026-08-14)

Evidence: dipy-1.12.1-cp311-cp311-macosx_11_0_arm64.whl; dipy-1.12.1-cp311-cp311-macosx_11_0_x86_64.whl; dipy-1.12.1-cp311-cp311-manylinux2014_aarch64.manylinux_2_17_aarch64.manylinux_2_28_aarch64.whl; dipy-1.12.1-cp311-cp311-manylinux2014_x86_64.manylinux_2_17_x86_64.manylinux_2_28_x86_64.whl; dipy-1.12.1-cp311-cp311-win_amd64.whl; dipy-1.12.1-cp312-cp312-macosx_11_0_arm64.whl; dipy-1.12.1-cp312-cp312-macosx_11_0_x86_64.whl; dipy-1.12.1-cp312-cp312-manylinux2014_aarch64.manylinux_2_17_aarch64.manylinux_2_28_aarch64.whl; dipy-1.12.1-cp312-cp312-manylinux2014_x86_64.manylinux_2_17_x86_64.manylinux_2_28_x86_64.whl; dipy-1.12.1-cp312-cp312-win_amd64.whl; dipy-1.12.1-cp313-cp313-macosx_11_0_arm64.whl; dipy-1.12.1-cp313-cp313-macosx_11_0_x86_64.whl; dipy-1.12.1-cp313-cp313-manylinux2014_aarch64.manylinux_2_17_aarch64.manylinux_2_28_aarch64.whl; dipy-1.12.1-cp313-cp313-manylinux2014_x86_64.manylinux_2_17_x86_64.manylinux_2_28_x86_64.whl; dipy-1.12.1-cp313-cp313-win_amd64.whl; dipy-1.12.1-cp314-cp314-macosx_11_0_arm64.whl; dipy-1.12.1-cp314-cp314-macosx_11_0_x86_64.whl; dipy-1.12.1-cp314-cp314-manylinux2014_aarch64.manylinux_2_17_aarch64.manylinux_2_28_aarch64.whl; dipy-1.12.1-cp314-cp314-manylinux2014_x86_64.manylinux_2_17_x86_64.manylinux_2_28_x86_64.whl; dipy-1.12.1-cp314-cp314-win_amd64.whl

Keywords: dipy, diffusionimaging, dti, tracking, tractography, diffusionmri, mri, tractometry, connectomics, brain, dipymri, microstructure, deeplearning, registration, segmentations, simulation, medical, imaging, brain, machinelearning, signalprocessing

Development Status :: 4 - BetaEnvironment :: ConsoleIntended Audience :: DevelopersIntended Audience :: Science/ResearchLicense :: OSI Approved :: BSD LicenseOperating System :: MacOSOperating System :: Microsoft :: WindowsOperating System :: OS IndependentOperating System :: POSIXOperating System :: UnixProgramming Language :: PythonProgramming Language :: Python :: 3Programming Language :: Python :: 3 :: OnlyProgramming Language :: Python :: 3.11Programming Language :: Python :: 3.12Programming Language :: Python :: 3.13Programming Language :: Python :: 3.14Topic :: Scientific/EngineeringTopic :: Software Development :: Libraries

Tags

diffusion MRI analysistractography fiber trackingDTI dMRI processingbrain diffusion imagingneuroimaging registrationconnectomics analysisdiffusion signal processing
neuroimagingdiffusion-mritractography

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