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cwltool

Common workflow language reference implementation

Worth itPyPI Scientific/EngineeringReleased Jul 2026294.7K downloads / mopermissive licensePure Python

Decision gist · record as of 2026-08-14

pure-Python wheel — cwltool-3.2.20260720092025-py3-none-any.whl
v3.2.20260720092025 · released 2026-07-20 · Python <3.15,>=3.10 · 16 runtime deps: requests, ruamel.yaml, rdflib, schema-salad, prov, mypy-extensions, psutil, coloredlogs

Yes. cwltool is the canonical reference implementation of an open standard, actively maintained, permissively licensed, and widely used in scientific computing. Install it if you need to execute portable workflows, validate CWL definitions, or integrate CWL workflows into Python applications. The main prerequisite is having a container engine available; without one, containerized workflow steps cannot run.AI-flagged interpretation of the facts on this page — verify before relying

Before you install

  • Requires a container engine (Docker, Podman, Singularity, or Apptainer) to execute containerized workflow steps; node.js recommended for evaluating CWL expressions.
  • Low install friction with a pure Python wheel distribution.
  • The package is actively maintained (last commit 2026-08-14, release 25 days ago) and supports current Python versions (3.10–3.14).

License · maintenance · safety

permissive license (permissive) — Licensed under Apache Software License (permissive), allowing commercial and private use with minimal restrictions.

last release 2026-07-20 (25 days) · last repo commit 2026-08-14 · 376 stars

0 known vulnerabilities (OSV.dev, 2026-08-14) · 294,687 downloads/mo, #7,944 on PyPI

Verify before relying

pip install cwltool

cwltool my_workflow.cwl my_inputs.yaml
  • Performance characteristics when executing large-scale workflows or handling thousands of tasks.
  • Specific memory and CPU overhead for workflow orchestration and validation.
  • Compatibility details with all supported container engines and their versions.
Same gist for agents: .md · .json

What it is and what it does

cwltool is the official reference implementation of the Common Workflow Language (CWL) standard, a specification for describing computational workflows in a portable, platform-agnostic way. It provides a command-line tool and Python library for parsing, validating, and executing CWL workflow definitions, allowing you to define complex scientific pipelines once and run them on different systems—from local machines to cloud platforms and high-performance computing clusters.

The tool integrates with container engines (Docker, Podman, Singularity, Apptainer, or udocker) to isolate and execute individual workflow steps, manages data flow between tasks, and handles resource allocation. It depends on schema-salad for CWL schema validation, rdflib for semantic data handling, prov for provenance tracking, and several utility libraries for logging, argument parsing, and visualization. The package is actively developed by the CWL project (a Software Freedom Conservancy member) and supports Python 3.10 through 3.14.

Use it for

  • Execute bioinformatics pipelines (genomics, proteomics) defined in CWL across different HPC clusters or cloud providers without modification.
  • Validate CWL workflow files for correctness before deployment in production environments.
  • Integrate scientific workflows into larger systems by using cwltool as a Python library to programmatically run and monitor CWL tasks.
  • Port existing workflows between institutional computing environments (local, cloud, or shared HPC) by leveraging CWL's platform-agnostic design.
  • Combine multiple containerized tools into reproducible multi-step workflows with explicit data dependencies and resource requirements.

Worth the install?

AI-flagged interpretation of the facts on this page. Verify before relying on it.

Worth it

Yes.

cwltool is the canonical reference implementation of an open standard, actively maintained, permissively licensed, and widely used in scientific computing. Install it if you need to execute portable workflows, validate CWL definitions, or integrate CWL workflows into Python applications. The main prerequisite is having a container engine available; without one, containerized workflow steps cannot run.

Install

cwltool on PyPI

Before you install

Low install friction with a pure Python wheel distribution. The package is actively maintained (last commit 2026-08-14, release 25 days ago) and supports current Python versions (3.10–3.14). It has 16 runtime dependencies, all widely available, with no known vulnerabilities.

Requires a container engine (Docker, Podman, Singularity, or Apptainer) to execute containerized workflow steps; node.js recommended for evaluating CWL expressions.

License in practice

Licensed under Apache Software License (permissive), allowing commercial and private use with minimal restrictions.

Quickstart

pip install cwltool

cwltool my_workflow.cwl my_inputs.yaml

Verify before relying

  • Performance characteristics when executing large-scale workflows or handling thousands of tasks.
  • Specific memory and CPU overhead for workflow orchestration and validation.
  • Compatibility details with all supported container engines and their versions.

Package facts

Licensepermissive license permissive
Python supportSupports the current Python release <3.15,>=3.10
Install frictionLow. Pure-Python wheel
Runtime dependencies
16 packages
requestsruamel.yamlrdflibschema-saladprovmypy-extensionspsutilcoloredlogspydotargcompletepyparsingcwl-utilsspythonrich-argparsepygmentstyping-extensions
MaintenanceActively maintained 25 days since the last release
Last repo commit
First released
Downloads294,687 / month, #7,944 on PyPI 30-day window, as of 2026-08-14
Known vulnerabilitiesNone known OSV.dev, checked 2026-08-14
Classifiers
Development Status :: 5 - Production/StableEnvironment :: ConsoleIntended Audience :: DevelopersIntended Audience :: Healthcare IndustryIntended Audience :: Science/ResearchLicense :: OSI Approved :: Apache Software LicenseNatural Language :: EnglishOperating System :: MacOS :: MacOS XOperating System :: POSIXOperating System :: POSIX :: LinuxProgramming Language :: Python :: 3Programming Language :: Python :: 3.10Programming Language :: Python :: 3.11Programming Language :: Python :: 3.12Programming Language :: Python :: 3.13Programming Language :: Python :: 3.14Topic :: Scientific/EngineeringTopic :: Scientific/Engineering :: AstronomyTopic :: Scientific/Engineering :: Atmospheric ScienceTopic :: Scientific/Engineering :: Bio-InformaticsTopic :: Scientific/Engineering :: Information AnalysisTopic :: Scientific/Engineering :: Medical Science Apps.Topic :: System :: Distributed ComputingTopic :: Utilities

Evidence: cwltool-3.2.20260720092025-py3-none-any.whl

Tags

Capabilities
workflow execution enginecommon workflow language runnerportable scientific workflowscwl workflow executorbioinformatics pipeline tooldistributed workflow managementcontainer-based workflow execution
Topics
workflow-orchestrationbioinformaticscontainerized-execution

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See also cwl-upgrader · cwltest · cwl-utils · apache-airflow · vcstool · apache-airflow-providers-singularity · prefect-docker · metaflow-prebuilt · schema-salad · cwsandbox