{"categories":[{"label":"Bio-Informatics","url":"https://skillfed.io/packages/category/scientific-engineering-bio-informatics"}],"enrichment":{"capability":"Python interface to g:Profiler toolkit for functional enrichment analysis, gene identifier conversion, and ortholog mapping across organisms.","skillfed_tags":["bioinformatics","gene-enrichment","unmaintained"],"use_cases":["Identify enriched Gene Ontology terms and biological pathways in a list of differentially expressed genes from RNA-seq.","Convert gene symbols to Entrez Gene IDs or other identifier systems for cross-database lookups.","Map human genes to their mouse orthologs for translating findings between model organisms.","Batch-process multiple gene lists with different enrichment parameters and combine results programmatically.","Integrate functional annotation into automated bioinformatics pipelines without manual web interface interaction."],"what_it_does":"gprofiler-official is the official Python 3 client for the g:Profiler toolkit, a web-based bioinformatics platform for functional analysis. It provides three main tools: g:GOSt (profile) performs enrichment analysis to identify statistically significant functional terms and gene annotations in your query; g:Convert maps gene identifiers between different namespaces (HGNC, Entrez, UniProt, etc.); and g:Orth finds orthologous genes in related organisms. The library communicates with the g:Profiler backend via requests and can optionally return results as pandas DataFrames.\n\nThe package is designed for researchers analyzing gene lists from experiments or computational predictions. It abstracts away HTTP communication and result parsing, letting you work directly with Python objects or structured data. The 1.0.x release introduced breaking API changes from the 0.3.x series, so existing code may require migration.","worth_installing":"Yes, if you need functional enrichment analysis and the g:Profiler backend remains operational. The low install friction and permissive license are favorable. However, the package is abandoned (last release 2019-04-02) and you should verify that the upstream g:Profiler service itself is still maintained and accessible before committing to a production workflow. No known security vulnerabilities."},"id":"gprofiler-official","links":{"html":"https://skillfed.io/packages/gprofiler-official","md":"https://skillfed.io/packages/gprofiler-official.md","pypi":"https://pypi.org/project/gprofiler-official/"},"maintenance":{"status":"abandoned"},"meta":{"latest_release":"2019-04-02","license_spdx":null,"license_treatment":"permissive","name":"gprofiler-official","python_support":"unspecified","summary":"Functional enrichment analysis and more via the g:Profiler toolkit"},"popularity":{"monthly_downloads":1384650,"position":3978,"tier":"top_5000"},"security":{"n_vulnerabilities":0},"version":"1.0.0"}