{"categories":[{"label":"Bio-Informatics","url":"https://skillfed.io/packages/category/scientific-engineering-bio-informatics"}],"enrichment":{"capability":"Provides a Python API to query and retrieve cell metadata and expression data from the CZ CELLxGENE Discover Census, a large-scale single-cell genomics dataset.","skillfed_tags":["single-cell-genomics","bioinformatics","data-portal"],"use_cases":["Query cell metadata across tissues and organisms to identify cells matching specific biological criteria for downstream analysis","Retrieve gene expression matrices for a subset of cells and genes to train machine learning models on reference data","Integrate Census data with local analysis pipelines by fetching pre-filtered cell populations as DataFrames","Explore cell type distributions and tissue composition across the human and mouse reference atlases"],"what_it_does":"cellxgene_census is a client library for accessing the CZ CELLxGENE Discover Census, a curated repository of single-cell genomics data. It abstracts the complexity of querying and retrieving cell metadata and gene expression measurements from a large distributed dataset, allowing researchers to filter cells by biological attributes (tissue, cell type, disease status, etc.) and fetch results as pandas DataFrames or other standard formats.\n\nThe package depends on tiledbsoma for efficient sparse array access, anndata for in-memory representation of single-cell data, and s3fs for cloud storage integration. It is designed for bioinformaticians and computational biologists who need programmatic access to reference single-cell datasets without managing raw files locally.","worth_installing":"Yes, if you work with single-cell genomics and need programmatic access to the CELLxGENE Census. The package is actively maintained, has no known vulnerabilities, uses a permissive MIT license, and installs with low friction. It is appropriate for research and production use. Install only if you have network access to the Census service and require Python 3.10 or later."},"id":"cellxgene-census","links":{"html":"https://skillfed.io/packages/cellxgene-census","md":"https://skillfed.io/packages/cellxgene-census.md","pypi":"https://pypi.org/project/cellxgene-census/"},"maintenance":{"status":"active"},"meta":{"latest_release":"2026-06-24","license_spdx":null,"license_treatment":"permissive","name":"cellxgene-census","python_support":"supports_current","summary":"API to facilitate the use of the CZ CELLxGENE Discover Census. For more information about the API and the project visit https://github.com/chanzuckerberg/cellxgene-census/"},"popularity":{"monthly_downloads":76903,"position":14581,"tier":"top_15000"},"security":{"n_vulnerabilities":0},"version":"1.18.0"}